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Fibronectin glomerulopathy

2 OMIM references -
1 associated gene
10 signs/symptoms

PROTEIN INTERACTIONS: 1

D,L-2-hydroxyglutaric aciduria

1 OMIM reference -
1 associated gene
No signs/symptoms info

Fibronectin glomerulopathy

D,L-2-hydroxyglutaric aciduria

(UniProt - OMIM)

(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	FN1	(0.72)	SLC25A1

Citations in the biomedical literature:

Fibronectin glomerulopathy		D,L-2-hydroxyglutaric aciduria
	Synonym(s): - GFND - Glomerulopathy with fibronectin deposits		Synonym(s): - Combined D-2-hydroxyglutaric acidemia and L-2-hydroxyglutaric acidemia - Combined D-2-hydroxyglutaric aciduria and L-2-hydroxyglutaric aciduria - D,L-2-HGA - D,L-2-hydroxyglutaric acidemia

	Classification (Orphanet): - Rare genetic disease - Rare renal disease		Classification (Orphanet): - Inborn errors of metabolism - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Diseases of the genitourinary system -		Classification (ICD10): - Endocrine, nutritional and metabolic diseases -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal recessive

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - No MeSH references

Fibronectin glomerulopathy
	Very frequent - Autosomal dominant inheritance - Chronic arterial hypertension - Edema of the legs / lower limbs - Functional anomalies of the kidney and the urinary tract - Hematuria / microhematuria - Nephrotic syndrome - Proteinuria - Renal failure - Renal glomerular defect / glomerulopathy Occasional - Intracranial / cerebral / meningeal hemorrhage
D,L-2-hydroxyglutaric aciduria
(no data available)